Exercise Training Evidence

Narrative Reviews

High-intensity interval training (HIT) for effective and time-efficient pre-surgical exercise interventions.
Weston M, Weston KL, Prentis JM, Snowden CP.
Perioper Med (Lond). 2016 Jan 14;5:2. doi: 10.1186/s13741-015-0026-8. eCollection 2016


Perioperative exercise training in elderly subjects. Best
Jack S, West M, Grocott MPW.
Pract Res Clin Anaesthesiol [. Elsevier Ltd; 2011;25(3):461-72.


Pre-operative Cardiopulmonary Exercise Testing and Prehabilitation.
Lisa ,Jack Sandy and Levett Denny.
Clinical Exercise Science, 1st edited by Andrew Scott and Christopher Gildlow, 02/2016: chapter 10; Routledge.


Nutrition and physical activity guidelines for cancer survivors.
Rock CL, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya KS, Schwartz AL, Bandera EV, Hamilton KK, Grant B, McCullough M, Byers T, Gansler T.
CA Cancer J Clin. 2012 Jul-Aug;62(4):243-74. doi: 10.3322/caac.21142. Epub 2012 Apr 26. Review. Erratum in: CA Cancer J Clin. 2013 May;63(3):215.


Identifying research priorities in anaesthesia and perioperative care: final report of the joint National Institute of Academic Anaesthesia/James Lind Alliance Research Priority Setting Partnership.
Boney O, Bell M, Bell N, Conquest A, Cumbers M, Drake S, Galsworthy M, Gath J, Grocott MP, Harris E, Howell S, Ingold A, Nathanson MH, Pinkney T, Metcalf L.
BMJ Open. 2015 Dec 16;5(12):e010006. doi: 10.1136/bmjopen-2015-010006


Exercise referral: the public health panacea for physical activity promotion? A critical perspective of exercise referral schemes; their development and evaluation
Dugdill L, Graham RC, McNair F.
Ergonomics. 2005 Sep 15-Nov 15;48(11-14):1390-410. Review


High-intensity aerobic exercise training improves the heart in health and disease.
Kemi OJ, Wisloff U.
J Cardiopulm Rehabil Prev. 2010 Jan-Feb;30(1):2-11. doi: 10.1097/HCR.0b013e3181c56b89. Review


Prehabilitation versus rehabilitation: a randomized control trial in patients undergoing colorectal resection for cancer.
Gillis C, Li C, Lee L, Awasthi R, Augustin B, Gamsa A, Liberman AS, Stein B, Charlebois P, Feldman LS, Carli F.
Anesthesiology. 2014 Nov;121(5):937-47. doi: 10.1097/ALN.0000000000000393.


Optimization of surgical outcomes with prehabilitation.
Santa Mina D, Scheede-Bergdahl C, Gillis C, Carli F.
Appl Physiol Nutr Metab. 2015 Sep;40(9):966-9. Review



High-intensity interval exercise training before abdominal aortic aneurysm repair (HIT-AAA): protocol for a randomised controlled feasibility trial.
Tew GA, Weston M, Kothmann E, Batterham AM, Gray J, Kerr K, Martin D, Nawaz S, Yates D, Danjoux G.
BMJ Open. 2014 Jan 10;4(1):e004094. doi: 10.1136/bmjopen-2013-004094..


Randomized clinical trial of prehabilitation before planned liver resection
Dunne DF, Jack S, Jones RP, Jones L, Lythgoe DT, Malik HZ, Poston GJ, Palmer DH, Fenwick SW.
Br J Surg. 2016 Apr;103(5):504-12. doi: 10.1002/bjs.10096. Epub 2016 Feb 11.


The effects of neoadjuvant chemoradiotherapy and an in-hospital exercise training programme on physical fitness and quality of life in locally advanced rectal cancer patients (The EMPOWER Trial): study protocol for a randomised controlled trial
Loughney L, West MA, Kemp GJ, Rossiter HB, Burke SM, Cox T, Barben CP, Mythen MG, Calverley P, Palmer DH, Grocott MP, Jack S.
Trials. 2016 Jan 13;17:24. doi: 10.1186/s13063-015-1149-4


Effect of prehabilitation on objectively measured physical fitness after neoadjuvant treatment in preoperative rectal cancer patients: A blinded interventional pilot study.
West MA, Loughney L, Lythgoe D, Barben CP, Sripadam R, Kemp GJ, et al.
Br J Anaesth. 2015;114(2):244-51.


The effect of neoadjuvant chemoradiotherapy on whole-body physical fitness and skeletal muscle mitochondrial oxidative phosphorylation in vivo in locally advanced rectal cancer patients--an observational pilot study
West MA, Loughney L, Lythgoe D, Barben CP, Adams VL, Bimson WE, Grocott MP, Jack S, Kemp GJ.
PLoS One. 2014 Dec 5;9(12):e111526.


Patients’ perceptions of quality of life during active treatment for locally advanced rectal cancer: The importance of preoperative exercise.
Burke SM, Brunet J, Sabiston CM, Jack S, Grocott MPW, West MA.
Support Care Cancer. 2013;21(12):3345-53.


Feasibility and preliminary efficacy of progressive resistance exercise training in lung cancer survivors.
Peddle-McIntyre CJ, Bell G, Fenton D, McCargar L, Courneya KS.
Lung Cancer. 2012 Jan;75(1):126-32.


The effects of neoadjuvant chemoradiotherapy on physical fitness and morbidity in rectal cancer surgery patients.
West MA, Loughney L, Barben CP, Sripadam R, Kemp GJ, Grocott MP, Jack S.
Eur J Surg Oncol. 2014 Nov;40(11):1421-8.


The effect of neoadjuvant chemotherapy on physical fitness and survival in patients undergoing oesophagogastric cancer surgery.
Jack S, West MA, Raw D, Marwood S, Ambler G, Cope TM, Shrotri M, Sturgess RP, Calverley PM, Ottensmeier CH, Grocott MP.
Eur J Surg Oncol. 2014 Oct;40(10):1313-20.


Effect of short-term exercise training on aerobic fitness in patients with abdominal aortic aneurysms: A pilot study.
Kothmann E, Batterham AM, Owen SJ, Turley AJ, Cheesman M, Parry A, et al.
Br J Anaesth. 2009;103(4):505-10.


Prehabilitation before total knee arthroplasty increases strength and function in older adults with severe osteoarthritis.
Swank AM, Kachelman JB, Bibeau W, Quesada PM, Nyland J, Malkani A, Topp RV.
J Strength Cond Res. 2011 Feb;25(2):318-25



Systematic Reviews

Preoperative aerobic exercise training in elective intra-cavity surgery: a systematic review.
O'Doherty AF, West M, Jack S, Grocott MP.
Br J Anaesth. 2013 May;110(5):679-89. doi: 10.1093/bja/aes514. Epub 2013 Feb 7. Review


Exercise intervention in people with cancer undergoing neoadjuvant cancer treatment and surgery: A systematic review.
Loughney L, West MA, Kemp GJ, Grocott MP, Jack S.
Eur J Surg Oncol. 2016 Jan;42(1):28-38. doi: 10.1016/j.ejso.2015.09.027. Epub 2015 Oct 23. Review


Exercise intervention in people with cancer undergoing adjuvant cancer treatment following surgery: A systematic review.
Loughney L, West MA, Kemp GJ, Grocott MP, Jack S.
Eur J Surg Oncol. 2015 Dec;41(12):1590-602. doi: 10.1016/j.ejso.2015.08.153. Epub 2015 Aug 29. Review


A systematic review of pre-surgical exercise intervention studies with cancer patients.
Singh F, Newton RU, Galvão DA, Spry N, Baker MK.
Surg Oncol. 2013 Jun;22(2):92-104. doi: 10.1016/j.suronc.2013.01.004. Epub 2013 Feb 19. Review.


A meta-analysis of exercise interventions among people treated for cancer
Conn VS, Hafdahl AR, Porock DC, McDaniel R, Nielsen PJ.
Support Care Cancer. 2006 Jul;14(7):699-712. Epub 2006 Jan 31. Erratum in: Support Care Cancer. 2007 Dec;15(12):1441-2


An update of controlled physical activity trials in cancer survivors: a systematic review and meta-analysis.
Speck RM, Courneya KS, Mâsse LC, Duval S, Schmitz KH.
J Cancer Surviv. 2010 Jun;4(2):87-100. doi: 10.1007/s11764-009-0110-5. Epub 2010 Jan 6. Review. Erratum in: J Cancer Surviv. 2011 Mar;5(1):112


Clinical exercise interventions in prostate cancer patients--a systematic review of randomized controlled trials.
Baumann FT, Zopf EM, Bloch W.
Support Care Cancer. 2012 Feb;20(2):221-33. doi: 10.1007/s00520-011-1271-0. Epub 2011 Oct 12. Review


Role of cardiopulmonary exercise testing as a risk-assessment method in patients undergoing intra-abdominal surgery: a systematic review.
Moran J, Wilson F, Guinan E, McCormick P, Hussey J, Moriarty J.
Br J Anaesth. 2016 Feb;116(2):177-91. doi: 10.1093/bja/aev454. Review.


Physical activity for cancer survivors: meta-analysis of randomised controlled trials.
Fong DY, Ho JW, Hui BP, Lee AM, Macfarlane DJ, Leung SS, Cerin E, Chan WY, Leung IP, Lam SH, Taylor AJ, Cheng KK.
BMJ. 2012 Jan 30;344:e70. doi: 10.1136/bmj.e70


Mechanism Reviews

The anti-inflammatory effect of exercise.
Petersen AM, Pedersen BK.
J Appl Physiol (1985). 2005 Apr;98(4):1154-62. Review.


The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease.
Gleeson M, Bishop NC, Stensel DJ, Lindley MR, Mastana SS, Nimmo MA.
Nat Rev Immunol. 2011 Aug 5;11(9):607-15. doi: 10.1038/nri3041